|作者：bystander 在 驴鸣镇 发贴, 来自 http://www.hjclub.org
So the researchers started taking blood samples from villagers in China who lived near some of the bat caves they'd been studying. Hongying Li is an ecologist with EcoHealth Alliance. She says there were any number of ways these people seemed at risk of inadvertently coming into contact with bat saliva, urine or poop. And people even visited the bat caves, says Li. The caves were a particularly popular hangout in the summer, when they provided respite from the heat.
She and her colleagues checked the villagers' blood for signs of recent infections with bat coronaviruses. The team did this again with people in some other rural areas. Each time, says Li, "we found coronaviruses that had already spilled over into the human population." These were multiple mini-outbreaks that had gone undetected. Olival says this discovery was a huge red flag: "The signal is there that these SARS-related viruses were jumping into people even if they weren't causing any noticeable disease."
“After five years of surveying bats in a cave in southern China’s Yunnan Province, Zhengli Shi and colleagues discovered 11 new strains of SARS-related viruses in horseshoe bats (especially in Rhinolophus sinicus). Within the strains, the researchers found all the genes to make a SARS coronavirus similar to the epidemic strain, says Shi, a virologist at the Wuhan Institute of Virology, Chinese Academy of Sciences.
These new strains are more similar to the human version of SARS than were previously identified bat viruses, says Matthew Frieman, a virologist at the University of Maryland in Baltimore.
The article, which was recently wiped from the Wuhan Institute of Virology’s website, also notes that Shi and her colleagues found that “several of the strains” could grow in human cells.
“By analyzing the new viruses’ complete genetic makeup, Shi and her colleagues retraced the steps that might have given rise to the original SARS virus. A few spots in the viruses’ DNA seem particularly prone to rearrangement, so remixing happens often. The study suggests that recombination between viruses has shaped the evolution of SARS, says Baric.
大家的关注点不一样。我比较关心疫苗的unintended consequences。Moderna多年来积极研发mRNA疫苗，但2020年以前从未有成功推出任何符合安全标准的产品。mRNA疫苗的发明者Robert Malone也三番四次作出警告，贸然拿实验阶段的疫苗，在疫情爆发期间大规模接种，是一场极高风险的赌博。
作者：bystander 在 驴鸣镇 发贴, 来自 http://www.hjclub.org